Life with Type 1 Diabetes,
medical research and the search for a cure

Path to a Cure is kindly supported by Novo Nordisk

Archive for April, 2010

JDRF Artificial Pancreas New artificial pancreas uses two hormones instead of oneThe JDRF Artificial Pancreas Consortium has made significant advancements in their quest to develop a safe and effective automated diabetes management system, with trials already showing it is possible to maintain healthy blood glucose levels in people with type 1 diabetes without the need for human intervention.

To date, the closed-loop systems tested have combined an insulin pump with glucose monitoring and complex computer programs designed to predict and activate insulin release as required. Whilst results of these trials have been overwhelmingly positive, researchers have found it to be more difficult than first anticipated to finely tune blood glucose levels – particularly when protecting patients against potentially dangerous hypoglycemia caused by too much insulin.

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2009 freedom award Boral & Macquarie joint winners of the Freedom AwardJDRF is proud to award the 2009 Freedom Award to joint recipients for the first time in the history of this prestigious award. These recipients are Boral Limited and Macquarie Group. The JDRF Freedom Award recognises the highest corporate fundraising organisation over a calendar year and represents a deep and significant partnership between these organisations and JDRF.

Combined staff and corporate donations from these organisations come to a staggering $920,000 – funds that will be invested in the best Australian medical research programs to find a cure for type 1 diabetes and its complications.

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dr pere santamaria New vaccine safely stops beta cell attackJDRF researchers from Canada show that a new vaccine can cure type 1 diabetes in mice and slow the onset of the condition in mice at risk of the disease.

Type 1 diabetes is caused when a persons own immune system attacks and destroys the insulin-producing cells in the pancreas. Whilst the precise trigger of this attack is still unproven, researchers do know that there are certain immune cells that play a more important role than others. The challenge is to target the “bad” cells without harming the good cells that protect us from day-to-day infections.

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cells Pancreas cells can convert to produce insulinJDRF researchers have shown for the first time that other pancreas cells can spontaneously re-program themselves to produce insulin without the need for complex genetic modification or surgical transplantation.

Under healthy conditions, beta cells regenerate slowly to respond to increased insulin requirements or to replace those lost by injury. In the case of type 1 diabetes however, the beta cells are destroyed faster than they can naturally regenerate.

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