Life with Type 1 Diabetes,
medical research and the search for a cure

Path to a Cure is kindly supported by Novo Nordisk

Posts Tagged ‘xenotransplantation’

beta Everything you need to know about... xenotransplantation What is xenotransplantation?

For type 1 diabetes, xenotransplantation involves taking insulin-producing islets from animals —in this case, pigs—and transplanting them into people. Pigs are considered the best species for xenotransplantation because pig organs are similar in size and physiology to human organs and pig insulin has been shown to work effectively in humans.

Earlier this year, the Australian government’s National Health and Medical Research Council lifted a moratorium on the clinical use of xenotransplantation. The ruling came after five years of research into the possible side effects of the technique, particularly the potential transmission of disease from animals to humans. It concluded that xenotransplantation research can proceed, given that researchers adhere to strict guidelines, and that the associated risks with xenotransplantation are minimal and acceptable given the potential benefits.

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islet cells JDRF funds research into pig islet transplantationJDRF has announced a one year industry partnership with an Australian company to support a clinical trial into the use of encapsulated pig islets to treat type 1 diabetes.

The trial, being conducted in New Zealand by Living Cell Technologies, involves eight adult patients with established type 1 diabetes and hypoglycemia unawareness – a constant inability to sense when blood glucose levels are dropping dangerously low.

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operating theatre Australia lifts ban on animal to human transplantsThe Australian National Health and Medical Research Council has lifted a five-year ban on the clinical use of xenotransplantation – a medical process involving the transplantation of animal tissue into humans to treat disease.

The ban was originally established by the NHMRC in 2004 to allow for further research into the possible side effects of the technique, particularly concerning the potential transmission of disease from animals to humans.

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